A medical examiner identified the victim as Monique Lofton, 34.
Lofton was a passenger in a 2014 Ford Escape being driven on I-94 northbound south of 130th street, police said.
At about 10:45 a.m., Lofton jumped from the moving vehicle which was being driven by a 55-year-old woman, police said.
After jumping, officials determined that she was struck by a vehicle which continued driving. Police were searching for that other vehicle.
After the incident the northbound Bishop Ford was closed from 10:45 a.m. until 2:15 p.m., police said.
Anyone with information is asked to call Illinois State Police at (847)294-4400.
The Chicago Tribune contributed to this report.