It happened Monday morning around 11 a.m.
Dispatch tells LEX 18 that the derailment shut down Office Street, E Lexington Street and Marimon Avenue.
They called the incident a "side derailment."
The scene has since been cleared and the engine that caused the traffic issues was sent on its way.
All roads are now open.
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Train derails in Harrodsburg (Nathan Justice, WTVQ, LLC)
Officials say sometime around noon Monday, a southbound Norfolk Southern train from Danville was traveling through downtown Harrodsburg when one of the locomotive’s trucks derailed.
The train was carrying 25 cars with two locomotives and had a two person crew. Cars were disconnected from the locomotive and then it was re-railed and was able to continue on its journey after about an hour-and-a-half.
No injuries or damage was reported, though there were plenty of traffic delays in downtown Harrodsburg.